When scientists first created the class of drugs that includes Ozempic, they told a tidy story about how the medications would work: The gut releases a hormone called GLP-1 that signals you’re full, so a drug that mimics GLP-1 could do the exact same thing, helping people eat less and lose weight.
How will Facebook celebrate its 20th birthday? Perhaps it will create one of those cute video montages they like to generate at significant moments. Starting with a tinkling piano soundtrack, a couple of breathless friend requests, and some self-conscious, tentative writing of “hello!” on other users’ walls, it might then pass quickly through moments of chronic oversharing, passive-aggressive, stalking of exes, and horrified untagging of yourself in unflattering photos.
For the 10 years they were together, Kristen de Marco and her terrier Gracie were inseparable. De Marco brought her dog to work each day, and routinely left dinners and parties early to rush home to her; she skipped her 20th high-school reunion because Gracie was sick and none of the available hotels could accommodate a dog.
TODAY, the third Monday of January, has come to be known in the UK as "Blue Monday", the most depressing day of the year. The idea originated in 2005 via a press release issued by a travel company. Using a formula accounting for factors like weather, debt, post-holiday gloom, failed resolutions, low motivation, and the need for change, they calculated this date to be the saddest day of the year.
A little more than a year ago, Elon Musk began his reign at Twitter with an elaborately staged pun. On Wednesday, October 26, 2022, he posted a tweet with a video that showed him carrying a sink through the lobby of the company’s San Francisco headquarters. “Entering Twitter HQ—let that sink in!” he wrote.
The millennial internet first died in 2015. I remember the day exactly because I was one of seven staffers, in addition to many more permalancers, at Gawker Media who were laid off as part of a company-wide restructuring. I received a message on Slack, was asked to join a meeting in a nearby conference room...
Cultural upheavals can be a riddle in real time. Trends that might seem obvious in hindsight are poorly understood in the present or not fathomed at all. We live in turbulent times now, at the tail end of a pandemic that killed millions and, for a period, reordered existence as we knew it. It marked, perhaps more than any other crisis in modern times, a new era, the world of the 2010s wrenched away for good.