There’s no such thing as a miracle cure for weight loss, but the latest obesity drugs seem to come pretty close. People who take Ozempic or other weekly shots belonging to a class known as GLP-1 agonists, after the gut hormone they mimic, can lose a fifth or more of their body weight in a year. Incessant “food noise” fueling the urge to eat suddenly goes silent.
Yes, you can get bad coffee in Vienna. Vienna is known for its beautiful cafés, where philosophers, poets, and scientists have found inspiration over endless cups of fantastic coffee for hundreds of years. Coffee is still at the heart of Viennese culture; the café is an extension of your living room, a place to meet friends or just read.
When scientists first created the class of drugs that includes Ozempic, they told a tidy story about how the medications would work: The gut releases a hormone called GLP-1 that signals you’re full, so a drug that mimics GLP-1 could do the exact same thing, helping people eat less and lose weight.
Thomé de Gamond’s plans for an underwater tunnel between England and France, produced for the World Exposition of 1867. The yellow circles, top left, represent an enormous spiral ramp allowing access to the tunnel from an international artificial island on the Varne sandbank — Source.