There’s no such thing as a miracle cure for weight loss, but the latest obesity drugs seem to come pretty close. People who take Ozempic or other weekly shots belonging to a class known as GLP-1 agonists, after the gut hormone they mimic, can lose a fifth or more of their body weight in a year. Incessant “food noise” fueling the urge to eat suddenly goes silent.
Far out on the Arabian Sea one night in February, 2018, Sheikha Latifa bint Mohammed Al Maktoum, the fugitive daughter of Dubai’s ruling emir, marvelled at the stars. The voyage had been rough. Since setting out by dinghy and Jet Ski a few days before, she had been swamped by powerful waves, soaking the belongings she’d stowed in her backpack; after clambering aboard the yacht she’d secured for her escape, she’d spent days racked with nausea as it pitched on the swell. But tonight the sea was calmer, and she felt the stirring of an unfamiliar sensation. She was free.